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Publications of the AACR
Most pediatric malignancies are developmental tumors arising from aberrant differentiation. In the September 1 issue of Clinical Cancer Research, Jun S. Wei et al. hypothesize that pediatric tumors exhibit cancer and tissue-specific microRNA expression profiles associating with development and tumorigenic process — profiles that could be used in diagnosis and prognosis. The authors show that pediatric cancers differentially express miRNAs specific to their origins and types and that the high expression of the OncomiR-1 host gene, MIRHG1, is significantly associated with aggressive neuroblastoma. Read the press release for this article Read the article (published OnlineFirst) Cancer Research Clinical Cancer Research Cancer Epidemiology, Biomarkers & Prevention Molecular Cancer Research Molecular Cancer Therapeutics NEW! Cancer Prevention Research Cancer Reviews Online NEW! Cancer Prevention Journals Portal AACR Meeting Abstracts Online Annual Meeting Education Book Submit a Paper
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